Finnell/Cabrera Birth Defects Laboratory
2021    2020    2019     2018    2017    2016    2015    2014     2013    2012    2011    2010    2009


Yang N, Wang L, Finnell RH, Li Z, Jin L, Zhang L, Cabrera RM, Ye R, Ren A. 2016. Levels of folate receptor autoantibodies in maternal and cord blood and risk of neural tube defects in a Chinese population. Birth Defects Res A Clin Mol Teratol. 2016 May 11. doi: 10.1002/bdra.23517. [Epub ahead of print]. PMID: 27166990

Fonteles CSR, Finnell RH, George TM, Harshbarger RJ. 2016. Craniosynostosis: Current conceptions and misconceptions. AIMS Genetics. 2016 Apr 3(1):99-129. doi: 10.3934/genet.2016.1.99. AIMS Genetics Review.

Denny KJ, Kelly CF, Kumar V, Witham KL, Cabrera RM, Finnell RH, Taylor SM, Jeannes A, Woodruff TM. 2016. Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects. Birth Defects Res A Clin Mol Teratol. 2016 Mar;106(3):201-207. doi: 10.1002/bdra.23483. Epub 2016 Feb 22. PMID: 26900104

Lei Y, Finnell RH. 2016. New Techniques for the Study of Neural Tube Defects. Adv Tech Biol Med. 2016 Feb;4(1). pii: 157. E pub 2015 Dec 26. PMID: 27066597



Hill DS, Cabrera R, Wallis Schultz D, Zhu H, Lu W, Finnell RH, Wlodarczyk BJ. Autism-Like Behavior and Epigenetic Changes Associated with Autism as Consequences of In Utero Exposure to Environmental Pollutants in a Mouse Model. Behav Neurol. 2015;2015:426263. doi: 10.1155/2015/426263. Epub 2015 Oct 26. PMID: 26586927

Wlodarczyk BJ, Ogle K, Lin LY, Bialer M, Finnell RH. Comparative teratogenicity analysis of valnoctamide, risperidone, and olanzapine in mice. Bipolar Disord. 2015 Aug 20. doi: 10.1111/bdi.12325. [Epub ahead of print] PMID: 26292082

Wang B, Jin L, Ren A, Yuan Y, Liu J, Li Z, Zhang L, Yi D, Wang LL, Zhang Y, Wang X, Tao S, Finnell RH. Correction to Levels of Polycyclic Aromatic Hydrocarbons in Maternal Serum and Risk of Neural Tube Defects in Offspring. Environ Sci Technol. 2015 Sep 1;49(17):10754-5. doi: 10.1021/acs.est.5b03471. Epub 2015 Aug 14. PMID: 26274604

Cantarel BL, Lei Y, Weaver D, Zhu H, Farrell A, Benstead-Hume G, Reese J, Finnell RH. Analysis of archived residual newborn screening blood spots after whole genome amplification. BMC Genomics. 2015 Aug 13;16(1):602. doi: 10.1186/s12864-015-1747-2. PMID: 26268606

Shawlot W, Vazquez-Chantada M, Wallingford JB, Finnell RH. Rfx2 is required for spermatogenesis in the mouse. Genesis. 2015 Aug 6. doi: 10.1002/dvg.22880. [Epub ahead of print] PMID: 26248850

Webber DM, MacLeod SL, Bamshad MJ, Shaw GM, Finnell RH, Shete SS, Witte JS, Erickson SW, Murphy LD, Hobbs C. Developments in our understanding of the genetic basis of birth defects. Birth Defects Res A Clin Mol Teratol. 2015 Aug;103(8):680-91. doi: 10.1002/bdra.23385. Epub 2015 May 28. PMID: 26033863

Mawasi H, Shekh-Ahmad T, Finnell RH, Wlodarczyk BJ, Bialer M. Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide--Amide derivatives of valproic acid. Epilepsy Behav. 2015 May;46:72-8. doi: 10.1016/j.yebeh.2015.02.040. Epub 2015 Apr 8. PMID: 25863940

Fathe K, Person MD, Finnell RH. The application of a chemical determination of N-homocysteinylation levels in developing mouse embryos: implication for folate responsive birth defects. J Nutr Biochem. 2015 Apr;26(4):312-8. doi: 10.1016/j.jnutbio.2014.10.004. Epub 2014 Nov 12. PMID: 25620692



Lei Y, Fathe K, McCartney D, Zhu H, Yang W, Ross ME, Shaw GM, Finnell RH. Rare LRP6 Variants Identified in Spina Bifida Patients. Hum Mutat. 2014 Dec 25. doi: 10.1002/humu.22750. [Epub ahead of print] PMID: 25546815

Yi D, Yuan Y, Jin L, Zhou G, Zhu H, Finnell RH, Ren A. Levels of PAH-DNA adducts in cord blood and cord tissue and the risk of fetal neural tube defects in a Chinese population. Neurotoxicology. 2014 Dec 15;46C:73-78. doi: 10.1016/j.neuro.2014.12.003. [Epub ahead of print] PMID: 25522656

Wang B, Jin L, Ren A, Yuan Y, Liu J, Li Z, Zhang L, Yi D, Wang L, Zhang Y, Wang X, Tao S, Finnell RH. Levels of Polycyclic Aromatic Hydrocarbons in Maternal Serum and Risk of Neural Tube Defects in Offspring. Environ Sci Technol. 2014 Dec 23. [Epub ahead of print] PMID: 25488567

Martínez-Uña M, Varela-Rey M, Mestre D, Fernández-Ares L, Fresnedo O, Fernandez-Ramos D, Juan VG, Martin-Guerrero I, García-Orad A, Luka Z, Wagner C, Lu SC, García-Monzón C, Finnell RH, Aurrekoetxea I, Buqué X, Martínez-Chantar ML, Mato JM, Aspichueta P. S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease. J Hepatol. 2014 Oct 18. pii: S0168-8278(14)00780-6. doi: 10.1016/j.jhep.2014.10.019. [Epub ahead of print] PMID: 25457203

Shekh-Ahmad T, Mawasi H, McDonough JH, Finnell RH, Wlodarczyk BJ, Yavin E, Bialer M. Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid. Epilepsia. 2014 Nov 29. doi: 10.1111/epi.12857. [Epub ahead of print] PMID: 25442425

Mitchell LE, Finnell RH. Papers from the Eighth International Neural Tube Defects Conference. Birth Defects Res A Clin Mol Teratol. 2014 Aug;100(8):561-2. doi: 10.1002/bdra.23289. No abstract available. PMID: 25155952

Hansler A, Chen Q, Gray JD, Ross ME, Finnell RH, Gross SS. Untargeted metabolite profiling of murine embryos to reveal metabolic perturbations associated with neural tube closure defects. Birth Defects Res A Clin Mol Teratol. 2014 Aug;100(8):623-32. doi: 10.1002/bdra.23272. Epub 2014 Aug 13. PMID: 25115437

Fathe K, Palacios A, Finnell RH. Brief report novel mechanism for valproate-induced teratogenicity. Birth Defects Res A Clin Mol Teratol. 2014 Aug;100(8):592-7. doi: 10.1002/bdra.23277. Epub 2014 Jul 26. PMID: 25066307

Tsurubuchi T, Allender EV, Siddiqui MR, Shim KW, Ichi S, Boshnjaku V, Mania-Farnell B, Xi G, Finnell RH, McLone DG, Tomita T, Mayanil CS. A critical role of noggin in developing folate-nonresponsive NTD in Fkbp8 -/- embryos. Childs Nerv Syst. 2014 Aug;30(8):1343-53. doi: 10.1007/s00381-014-2428-1. Epub 2014 May 10. PMID: 24817375

Lei Y, Zhu H, Yang W, Ross ME, Shaw GM, Finnell RH. Identification of novel CELSR1 mutations in spina bifida. PLoS One. 2014 Mar 14;9(3):e92207. doi: 10.1371/journal.pone.0092207. eCollection 2014. PMID: 24632739

Wlodarczyk BJ, Zhu H, Finnell RH. Mthfr gene ablation enhances susceptibility to arsenic prenatal toxicity. Toxicol Appl Pharmacol. 2014 Feb 15;275(1):22-7. doi: 10.1016/j.taap.2013.12.014. Epub 2013 Dec 30. PMID: 24384392

Lupo PJ, Mitchell LE, Canfield MA, Shaw GM, Olshan AF, Finnell RH, Zhu H; National Birth Defects Prevention Study. Maternal-fetal metabolic gene-gene interactions and risk of neural tube defects. Mol Genet Metab. 2014 Jan;111(1):46-51. doi: 10.1016/j.ymgme.2013.11.004. Epub 2013 Nov 18. PMID: 24332798

Shekh-Ahmad T, Hen N, Yagen B, McDonough JH, Finnell RH, Wlodarczyk BJ, Bialer M. Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential. Epilepsia. 2014 Feb;55(2):353-61. doi: 10.1111/epi.12480. Epub 2013 Dec 6. PMID: 24313671



Denny KJ, Jeanes A, Fathe K, Finnell RH, Taylor SM, Woodruff TM. Neural tube defects, folate, and immune modulation. Birth Defects Res A Clin Mol Teratol. 2013 Sept;97(9):602-9. doi: 10.1002/bdra.23177. Review. PMID: 24078477

Lei Y, Zhu H, Duhon C, Yang W, Ross ME, Shaw GM, Finnell RH. Mutations in planar cell polarity gene SCRIB are associated with spina bifida. PLoS One. 2013 Jul 26;8(7):e69262. doi: 10.1371/journal.pone.0069262. Print 2013. PMID: 23922697

Agopian AJ, Bhalla AD, Boerwinkle E, Finnell RH, Grove ML, Hixson JE, Shimmin LC, Sewda A, Stuart C, Zhong Y, Zhu H, Mitchell LE. Exon sequencing of PAX3 and T (brachyury) in cases with spina bifida. Birth Defects Res A Clin Mol Teratol. 2013 Sep;97(9):597-601. doi: 10.1002/bdra.23163. Epub 2013 Aug 2. PMID: 23913553

Hen N, Shekh-Ahmad T, Yagen B, McDonough JH, Finnell RH, Wlodarczyk B, Bialer M. Stereoselective Pharmacodynamic and Pharmacokinetic Analysis of sec-Butyl-propylacetamide (SPD), a New CNS-Active Derivative of Valproic Acid with Unique Activity against Status Epilepticus. J Med Chem. Aug 22;56(16):6467-77. doi: 10.1021/jm4007565. Epub 2013 Aug 7. PMID: 23879329

Tabler JM, Barrell WB, Szabo-Rogers HL, Healy C, Yeung Y, Perdiguero EG, Schulz C, Yannakoudakis BZ, Mesbahi A, Wlodarczyk B, Geissmann F, Finnell RH, Wallingford JB, Liu KJ. Fuz Mutant Mice Reveal Shared Mechanisms between Ciliopathies and FGF-Related Syndromes. Dev Cell. 2013 Jun 24;25(6):623-35. doi: 10.1016/j.devcel.2013.05.021. PMID: 23806618

Martínez-Uña M, Varela-Rey M, Cano A, Fernández-Ares L, Beraza N, Aurrekoetxea I, Martínez-Arranz I, García-Rodríguez JL, Buqué X, Mestre D, Luka Z, Wagner C, Alonso C, Finnell RH, Lu SC, Martínez-Chantar ML, Aspichueta P, Mato JM. Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis. Hepatology. 2013 Mar 16. doi: 10.1002/hep.26399. PMID: 23505042

Wallingford JB, Niswander LA, Shaw GM, Finnell RH. The continuing challenge of understanding, preventing, and treating neural tube defects. Science. 2013 Mar 1;339(6123):1222002. doi: 10.1126/science.1222002. Review. PMID: 23449594

Lai SC, Nakayama Y, Sequeira JM, Wlodarczyk BJ, Cabrera RM, Finnell RH, Bottiglieri T, Quadros EV. The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system. FASEB J. 2013 Jun;27(6):2468-75. doi: 10.1096/fj.12-219055. Epub 2013 Feb 21. PMID: 23430977

Denny KJ, Coulthard LG, Jeanes A, Lisgo S, Simmons DG, Callaway LK, Wlodarczyk B, Finnell RH, Woodruff TM, Taylor SM. C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice. J Immunol. 2013 Apr 1;190(7):3493-9. doi: 10.4049/jimmunol.1203072. Epub 2013 Feb 18. PMID: 23420882

Farkas SA, Böttiger AK, Isaksson HS, Finnell RH, Ren A, Nilsson TK. Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with  hyperhomocysteinemia. Epigenetics. 2013 Mar;8(3):303-16. doi: 10.4161/epi.23988. Epub 2013 Feb 15. PMID: 23417011

Yuan Y, Jin L, Wang L, Li Z, Zhang L, Zhu H, Finnell RH, Zhou G, Ren A. Levels of PAH-DNA adducts in placental tissue and the risk of fetal neural tube defects in a Chinese population. Reprod Toxicol. 2013 Jun;37:70-5. doi: 10.1016/j.reprotox.2013.01.008. Epub 2013 Feb 15. PMID: 23416326

Denny KJ, Coulthard LG, Finnell RH, Callaway LK, Taylor SM, Woodruff TM. Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia. J Reprod Immunol. 2013 Apr;97(2):211-6. doi:10.1016/j.jri.2012.11.006. Epub 2013 Feb 14. PMID: 23415845

Wang X, Cabrera RM, Li Y, Miller DS, Finnell RH. Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice. FASEB J. 2013 Mar;27(3):1167-75. doi: 10.1096/fj.12-218495. Epub 2012 Dec 4. PMID: 23212123