FinnellLab

Publications

 Finnell Birth Defects Laboratory
2019

 

Lei Y, Kim SE, Chen Z, Cao X, Zhu H, Yang W, Shaw GM, Zheng Y, Zhang T, Wang HY, Finnell RH.
Variants identified in PTK7 associated with neural tube defects.
Mol Genet Genomic Med. 2019 Apr;7(4):e00584. doi: 10.1002/mgg3.584. Epub 2019 Jan 28.
PMID:30689296

Kim SE, Lei Y, Hwang SH, Wlodarczyk BJ, Mukhopadhyay S, Shaw GM, Ross ME, Finnell RH.
Dominant negative GPR161 rare variants are risk factors of human spina bifida.
Hum Mol Genet. 2019 Jan 15;28(2):200-208. doi: 10.1093/hmg/ddy339.
PMID:30256984

2018

 

Avagliano L, Massa V, George TM, Qureshy S, Bulfamante GP, Finnell RH.
Overview on neural tube defects: From development to physical characteristics.
Birth Defects Res. 2018 Nov 12. doi: 10.1002/bdr2.1380. [Epub ahead of print] Review.
PMID:30421543

Conde-Vancells J, Vazquez-Chantada M, McCollum CW, Bondesson M, Kalasekar SM, Wlodarczyk BJ, Gustafsson JÅ, Cabrera RM, Finnell RH.
Combining mouse embryonic stem cells and zebrafish embryos to evaluate developmental toxicity of chemical exposure.
Reprod Toxicol. 2018 Oct;81:220-228. doi: 10.1016/j.reprotox.2018.07.080. Epub 2018 Aug 10.
PMID:30103011

Kim J, Lei Y, Guo J, Kim SE, Wlodarczyk BJ, Cabrera RM, Lin YL, Nilsson TK, Zhang T, Ren A, Wang L, Yuan Z, Zheng YF, Wang HY, Finnell RH.
Formate rescues neural tube defects caused by mutations in Slc25a32.
Proc Natl Acad Sci U S A. 2018 May 1;115(18):4690-4695. doi: 10.1073/pnas.1800138115. Epub 2018 Apr 16.
PMID:29666258

2017

 

Toriyama M, Toriyama M, Wallingford JB, Finnell RH.
Folate-dependent methylation of septins governs ciliogenesis during neural tube closure.
FASEB J. 2017 Aug;31(8):3622-3635. doi: 10.1096/fj.201700092R. Epub 2017 Apr 21.
PMID:28432198

Ross ME, Mason CE, Finnell RH.
Genomic approaches to the assessment of human spina bifida risk.
Birth Defects Res. 2017 Jan 30;109(2):120-128. doi: 10.1002/bdra.23592. Review.
PMID:27883265

2016

 

Yang N, Wang L, Finnell RH, Li Z, Jin L, Zhang L, Cabrera RM, Ye R, Ren A.
Levels of folate receptor autoantibodies in maternal and cord blood and risk of neural tube defects in a Chinese population.
Birth Defects Res A Clin Mol Teratol. 2016 May 11. doi: 10.1002/bdra.23517. [Epub ahead of print].
PMID: 27166990   

Fonteles CSR, Finnell RH, George TM, Harshbarger RJ.
Craniosynostosis: Current conceptions and misconceptions.
AIMS Genetics. 2016 Apr 3(1):99-129. doi: 10.3934/genet.2016.1.99.
AIMS Genetics Review    

Denny KJ, Kelly CF, Kumar V, Witham KL, Cabrera RM, Finnell RH, Taylor SM, Jeannes A, Woodruff TM.
Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects.
Birth Defects Res A Clin Mol Teratol. 2016 Mar;106(3):201-207. doi: 10.1002/bdra.23483. Epub 2016 Feb 22.
PMID: 26900104    

Lei Y, Finnell RH.
New Techniques for the Study of Neural Tube Defects.
Adv Tech Biol Med. 2016 Feb;4(1). pii: 157. E pub 2015 Dec 26.
PMID: 27066597   

2015

 

Hill DS, Cabrera R, Wallis Schultz D, Zhu H, Lu W, Finnell RH, Wlodarczyk BJ.
Autism-Like Behavior and Epigenetic Changes Associated with Autism as Consequences of In Utero Exposure to Environmental Pollutants in a Mouse Model.
Behav Neurol. 2015;2015:426263. doi: 10.1155/2015/426263. Epub 2015 Oct 26.
PMID: 26586927    

Wlodarczyk BJ, Ogle K, Lin LY, Bialer M, Finnell RH.
Comparative teratogenicity analysis of valnoctamide, risperidone, and olanzapine in mice.
Bipolar Disord. 2015 Aug 20. doi: 10.1111/bdi.12325. [Epub ahead of print]
PMID: 26292082    

Wang B, Jin L, Ren A, Yuan Y, Liu J, Li Z, Zhang L, Yi D, Wang LL, Zhang Y, Wang X, Tao S, Finnell RH.
Correction to Levels of Polycyclic Aromatic Hydrocarbons in Maternal Serum and Risk of Neural Tube Defects in Offspring.
Environ Sci Technol. 2015 Sep 1;49(17):10754-5. doi: 10.1021/acs.est.5b03471. Epub 2015 Aug 14. No abstract available.
PMID: 26274604    

Cantarel BL, Lei Y, Weaver D, Zhu H, Farrell A, Benstead-Hume G, Reese J, Finnell RH.
Analysis of archived residual newborn screening blood spots after whole genome amplification.
BMC Genomics. 2015 Aug 13;16(1):602. doi: 10.1186/s12864-015-1747-2.
PMID: 26268606    

Shawlot W, Vazquez-Chantada M, Wallingford JB, Finnell RH.
Rfx2 is required for spermatogenesis in the mouse.
Genesis. 2015 Aug 6. doi: 10.1002/dvg.22880. [Epub ahead of print]
PMID: 26248850    

Webber DM, MacLeod SL, Bamshad MJ, Shaw GM, Finnell RH, Shete SS, Witte JS, Erickson SW, Murphy LD, Hobbs C.
Developments in our understanding of the genetic basis of birth defects.
Birth Defects Res A Clin Mol Teratol. 2015 Aug;103(8):680-91. doi: 10.1002/bdra.23385. Epub 2015 May 28.
PMID: 26033863    

Mawasi H, Shekh-Ahmad T, Finnell RH, Wlodarczyk BJ, Bialer M.
Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide--Amide derivatives of valproic acid.
Epilepsy Behav. 2015 May;46:72-8. doi: 10.1016/j.yebeh.2015.02.040. Epub 2015 Apr 8.
PMID: 25863940    

Fathe K, Person MD, Finnell RH.
The application of a chemical determination of N-homocysteinylation levels in developing mouse embryos: implication for folate responsive birth defects.
J Nutr Biochem. 2015 Apr;26(4):312-8. doi: 10.1016/j.jnutbio.2014.10.004. Epub 2014 Nov 12.
PMID: 25620692    

2014

 

Lei Y, Fathe K, McCartney D, Zhu H, Yang W, Ross ME, Shaw GM, Finnell RH.
Rare LRP6 Variants Identified in Spina Bifida Patients.
Hum Mutat. 2014 Dec 25. doi: 10.1002/humu.22750. [Epub ahead of print]
PMID: 25546815    

Yi D, Yuan Y, Jin L, Zhou G, Zhu H, Finnell RH, Ren A.
Levels of PAH-DNA adducts in cord blood and cord tissue and the risk of fetal neural tube defects in a Chinese population.
Neurotoxicology. 2014 Dec 15;46C:73-78. doi: 10.1016/j.neuro.2014.12.003. [Epub ahead of print]
PMID: 25522656    

Wang B, Jin L, Ren A, Yuan Y, Liu J, Li Z, Zhang L, Yi D, Wang L, Zhang Y, Wang X, Tao S, Finnell RH.
Levels of Polycyclic Aromatic Hydrocarbons in Maternal Serum and Risk of Neural Tube Defects in Offspring.
Environ Sci Technol. 2014 Dec 23. [Epub ahead of print]
PMID: 25488567    

Martínez-Uña M, Varela-Rey M, Mestre D, Fernández-Ares L, Fresnedo O, Fernandez-Ramos D, Juan VG, Martin-Guerrero I, García-Orad A, Luka Z, Wagner C, Lu SC, García-Monzón C, Finnell RH, Aurrekoetxea I, Buqué X, Martínez-Chantar ML, Mato JM, Aspichueta P.
S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease.
J Hepatol. 2014 Oct 18. pii: S0168-8278(14)00780-6. doi: 10.1016/j.jhep.2014.10.019. [Epub ahead of print]
PMID: 25457203    

Shekh-Ahmad T, Mawasi H, McDonough JH, Finnell RH, Wlodarczyk BJ, Yavin E, Bialer M.
Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid.
Epilepsia. 2014 Nov 29. doi: 10.1111/epi.12857. [Epub ahead of print]
PMID: 25442425    

Mitchell LE, Finnell RH.
Papers from the Eighth International Neural Tube Defects Conference.
Birth Defects Res A Clin Mol Teratol. 2014 Aug;100(8):561-2. doi: 10.1002/bdra.23289. No abstract available.
PMID: 25155952    

Hansler A, Chen Q, Gray JD, Ross ME, Finnell RH, Gross SS.
Untargeted metabolite profiling of murine embryos to reveal metabolic perturbations associated with neural tube closure defects.
Birth Defects Res A Clin Mol Teratol. 2014 Aug;100(8):623-32. doi: 10.1002/bdra.23272. Epub 2014 Aug 13.
PMID: 25115437    

Fathe K, Palacios A, Finnell RH.
Brief report novel mechanism for valproate-induced teratogenicity.
Birth Defects Res A Clin Mol Teratol. 2014 Aug;100(8):592-7. doi: 10.1002/bdra.23277. Epub 2014 Jul 26.
PMID: 25066307    

Tsurubuchi T, Allender EV, Siddiqui MR, Shim KW, Ichi S, Boshnjaku V, Mania-Farnell B, Xi G, Finnell RH, McLone DG, Tomita T, Mayanil CS.
A critical role of noggin in developing folate-nonresponsive NTD in Fkbp8 -/- embryos.
Childs Nerv Syst. 2014 Aug;30(8):1343-53. doi: 10.1007/s00381-014-2428-1. Epub 2014 May 10.
PMID: 24817375    

Lei Y, Zhu H, Yang W, Ross ME, Shaw GM, Finnell RH.
Identification of novel CELSR1 mutations in spina bifida.
PLoS One. 2014 Mar 14;9(3):e92207. doi: 10.1371/journal.pone.0092207. eCollection 2014.
PMID: 24632739    

Wlodarczyk BJ, Zhu H, Finnell RH.
Mthfr gene ablation enhances susceptibility to arsenic prenatal toxicity.
Toxicol Appl Pharmacol. 2014 Feb 15;275(1):22-7. doi: 10.1016/j.taap.2013.12.014. Epub 2013 Dec 30.
PMID: 24384392    

Lupo PJ, Mitchell LE, Canfield MA, Shaw GM, Olshan AF, Finnell RH, Zhu H; National Birth Defects Prevention Study.
Maternal-fetal metabolic gene-gene interactions and risk of neural tube defects.
Mol Genet Metab. 2014 Jan;111(1):46-51. doi: 10.1016/j.ymgme.2013.11.004. Epub 2013 Nov 18
PMID: 24332798    

Shekh-Ahmad T, Hen N, Yagen B, McDonough JH, Finnell RH, Wlodarczyk BJ, Bialer M.
Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential.
Epilepsia. 2014 Feb;55(2):353-61. doi: 10.1111/epi.12480. Epub 2013 Dec 6.
PMID: 24313671

2013

 

Denny KJ, Jeanes A, Fathe K, Finnell RH, Taylor SM, Woodruff TM.
Neural tube defects, folate, and immune modulation.
Birth Defects Res A Clin Mol Teratol. 2013 Sept;97(9):602-9. doi: 10.1002/bdra.23177. Review.
PMID: 24078477    

Lei Y, Zhu H, Duhon C, Yang W, Ross ME, Shaw GM, Finnell RH.
Mutations in planar cell polarity gene SCRIB are associated with spina bifida.
PLoS One. 2013 Jul 26;8(7):e69262. doi: 10.1371/journal.pone.0069262. Print 2013.
PMID: 23922697    

Agopian AJ, Bhalla AD, Boerwinkle E, Finnell RH, Grove ML, Hixson JE, Shimmin LC, Sewda A, Stuart C, Zhong Y, Zhu H, Mitchell LE.
Exon sequencing of PAX3 and T (brachyury) in cases with spina bifida.
Birth Defects Res A Clin Mol Teratol. 2013 Sep;97(9):597-601. doi: 10.1002/bdra.23163. Epub 2013 Aug 2.
PMID: 23913553    

Hen N, Shekh-Ahmad T, Yagen B, McDonough JH, Finnell RH, Wlodarczyk B, Bialer M.
Stereoselective Pharmacodynamic and Pharmacokinetic Analysis of sec-Butyl-propylacetamide (SPD), a New CNS-Active Derivative of Valproic Acid with Unique Activity against Status Epilepticus.
J Med Chem. Aug 22;56(16):6467-77. doi: 10.1021/jm4007565. Epub 2013 Aug 7.
PMID: 23879329    

Tabler JM, Barrell WB, Szabo-Rogers HL, Healy C, Yeung Y, Perdiguero EG, Schulz C, Yannakoudakis BZ, Mesbahi A, Wlodarczyk B, Geissmann F, Finnell RH, Wallingford JB, Liu KJ.
Fuz Mutant Mice Reveal Shared Mechanisms between Ciliopathies and FGF-Related Syndromes.
Dev Cell. 2013 Jun 24;25(6):623-35. doi: 10.1016/j.devcel.2013.05.021.
PMID: 23806618    

Martínez-Uña M, Varela-Rey M, Cano A, Fernández-Ares L, Beraza N, Aurrekoetxea I, Martínez-Arranz I, García-Rodríguez JL, Buqué X, Mestre D, Luka Z, Wagner C, Alonso C, Finnell RH, Lu SC, Martínez-Chantar ML, Aspichueta P, Mato JM.
Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis.
Hepatology. 2013 Mar 16. doi: 10.1002/hep.26399.
PMID: 23505042    

Wallingford JB, Niswander LA, Shaw GM, Finnell RH.
The continuing challenge of understanding, preventing, and treating neural tube defects.
Science. 2013 Mar 1;339(6123):1222002. doi: 10.1126/science.1222002. Review.
PMID: 23449594    

Lai SC, Nakayama Y, Sequeira JM, Wlodarczyk BJ, Cabrera RM, Finnell RH, Bottiglieri T, Quadros EV.
The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system.
FASEB J. 2013 Jun;27(6):2468-75. doi: 10.1096/fj.12-219055. Epub 2013 Feb 21.
PMID: 23430977    

Denny KJ, Coulthard LG, Jeanes A, Lisgo S, Simmons DG, Callaway LK, Wlodarczyk B, Finnell RH, Woodruff TM, Taylor SM.
C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice.
J Immunol. 2013 Apr 1;190(7):3493-9. doi: 10.4049/jimmunol.1203072. Epub 2013 Feb 18.
PMID: 23420882    

Farkas SA, Böttiger AK, Isaksson HS, Finnell RH, Ren A, Nilsson TK.
Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia.
Epigenetics. 2013 Mar;8(3):303-16. doi: 10.4161/epi.23988. Epub 2013 Feb 15.
PMID: 23417011    

Yuan Y, Jin L, Wang L, Li Z, Zhang L, Zhu H, Finnell RH, Zhou G, Ren A.
Levels of PAH-DNA adducts in placental tissue and the risk of fetal neural tube defects in a Chinese population.
Reprod Toxicol. 2013 Jun;37:70-5. doi: 10.1016/j.reprotox.2013.01.008. Epub 2013 Feb 15.
PMID: 23416326    

Denny KJ, Coulthard LG, Finnell RH, Callaway LK, Taylor SM, Woodruff TM.
Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia.
J Reprod Immunol. 2013 Apr;97(2):211-6. doi:10.1016/j.jri.2012.11.006. Epub 2013 Feb 14.
PMID: 23415845    

Wang X, Cabrera RM, Li Y, Miller DS, Finnell RH.
Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice.
FASEB J. 2013 Mar;27(3):1167-75. doi: 10.1096/fj.12-218495. Epub 2012 Dec 4.
PMID: 23212123    

2012

 

Lupo PJ, Chapa C, Nousome D, Duhon C, Canfield MA, Shaw GM, Finnell RH, Zhu H.
A GCH1 haplotype and risk of neural tube defects in the National Birth Defects Prevention Study.
Mol Genet Metab. 2012 Nov;107(3):592-595. doi: 10.1016/j.ymgme.2012.09.020. Epub 2012 Sep 25.
PMID: 23059057    

Cabrera RM, Finnell RH, Zhu H, Shaw GM, Wlodarczyk BJ.
Transcriptional analyses of two mouse models of spina bifida.
Birth Defects Res A Clin Mol Teratol. 2012 Oct;94(10):782-9. doi: 10.1002/bdra.23081. Epub 2012 Sep 28.
PMID: 23024056    

Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH et al.
The mammalian gene function resource: the international knockout mouse consortium.
Mamm Genome. 2012 Oct;23(9-10):580-6. doi: 10.1007/s00335-012-9422-2. Epub 2012 Sep 12.
PMID: 22968824    

Etheredge AJ, Finnell RH, Carmichael SL, Lammer EJ, Zhu H, Mitchell LE, Shaw GM.
Maternal and infant gene-folate interactions and the risk of neural tube defects.
Am J Med Genet A. 2012 Oct;158A(10):2439-46. doi: 10.1002/ajmg.a.35552. Epub 2012 Aug 17.
PMID: 22903727    

Zhu H, Yang W, Shaw N, Perloff S, Carmichael SL, Finnell RH, Shaw GM, Lammer EJ.
Thymidylate synthase polymorphisms and risk of conotruncal heart defects.
Am J Med Genet A. 2012 Sep;158A(9):2194-203. doi: 10.1002/ajmg.a.35310. Epub 2012 Aug 7.
PMID: 22887475    

Wlodarczyk BJ, Palacios AM, George TM, Finnell RH.
Antiepileptic drugs and pregnancy outcomes.
Am J Med Genet A. 2012 Jun 18. doi: 10.1002/ajmg.a.35438.
PMID: 22711424    

Wallis D, Hill DS, Mendez IA, Abbott LC, Finnell RH, Wellman PJ, Setlow B.
Initial characterization of mice null for Lphn3, a gene implicated in ADHD and addiction.
Brain Res. 2012 Jun 29;1463:85-92. Epub 2012 May 7.
PMID: 22575564    

Zhu H, Yang W, Lu W, Etheredge AJ, Lammer EJ, Finnell RH, Carmichael SL, Shaw GM.
Gene variants in the folate-mediated one-carbon metabolism (FOCM) pathway as risk factors for conotruncal heart defects.
Am J Med Genet A. 2012 May;158A(5):1124-34. doi: 10.1002/ajmg.a.35313. Epub 2012 Apr 11.
PMID:22495907    

Paschaki M, Lin SC, Wong RL, Finnell RH, Dollé P, Niederreither K.
Retinoic acid-dependent signaling pathways and lineage events in the developing mouse spinal cord.
PLoS One. 2012;7(3):e32447. Epub 2012 Mar 2.
PMID: 22396766    

Lupo PJ, Langlois PH, Reefhuis J, Lawson CC, Symanski E, Desrosiers TA, Khodr ZG, Agopian AJ, Waters MA, Duwe KN, Finnell RH, Mitchell LE, Moore CA, Romitti PA, Shaw GM
Maternal Occupational Exposure to Polycyclic Aromatic Hydrocarbons: Effects on Gastroschisis among Offspring in the National Birth Defects Prevention Study.
Environ Health Perspect. 2012 Jun;120(6):910-5. Epub 2012 Feb 13.
PMID: 22330681    

Psychoyos D, Vinod KY, Cao J, Xie S, Hyson RL, Wlodarczyk B, He W, Cooper TB, Hungund BL, Finnell RH.
Cannabinoid receptor 1 signaling in embryo neurodevelopment.
Birth Defects Res B Dev Reprod Toxicol. 2012 Apr;95(2):137-50. doi: 10.1002/bdrb.20348. Epub 2012 Feb 6.
PMID: 22311661    

2011

 

Pessah N, Yagen B, Hen N, Shimshoni JA, Wlodarczyk B, Finnell RH, Bialer M.
Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid.
Epilepsy Behav. 2011 Nov;22(3):461-8. doi: 10.1016/j.yebeh.2011.08.026. Epub 2011 Sep 29.
PMID: 21959082    

Ren A, Qiu X, Jin L, Ma J, Li Z, Zhang L, Zhu H, Finnell RH, Zhu T.
Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects.
Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12770-5. doi: 10.1073/pnas.1105209108. Epub 2011 Jul 18.
PMID: 21768370    

Wlodarczyk BJ, Palacios AM, Chapa CJ, Zhu H, George TM, Finnell RH.
Genetic basis of susceptibility to teratogen induced birth defects.
Am J Med Genet C Semin Med Genet. 2011 Aug 15;157C(3):215-26. doi: 10.1002/ajmg.c.30314. Epub 2011 Jul 15.
PMID: 21766441    

Boyles AL, Ballard JL, Gorman EB, McConnaughey DR, Cabrera RM, Wilcox AJ, Lie RT, Finnell RH.
Association between inhibited binding of folic acid to folate receptor alpha in maternal serum and folate-related birth defects in Norway.
Hum Reprod. 2011 Aug;26(8):2232-8. doi: 10.1093/humrep/der144. Epub 2011 May 15.
PMID: 21576080    

Wang J, Chen L, Wen S, Zhu H, Yu W, Moskowitz IP, Shaw GM, Finnell RH, Schwartz RJ.
Defective sumoylation pathway directs congenital heart disease.
Birth Defects Res A Clin Mol Teratol. 2011 Jun;91(6):468-76. doi: 10.1002/bdra.20816. Epub 2011 May 11.
PMID: 21563299    

Salojin KV, Cabrera RM, Sun W, Chang WC, Lin C, Duncan L, Platt KA, Read R, Vogel P, Liu Q, Finnell RH, Oravecz T.
A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency.
Blood. 2011 May 5;117(18):4895-904. doi: 10.1182/blood-2010-04-279653. Epub 2011 Feb 23.
PMID: 21346251    

Blanton SH, Henry RR, Yuan Q, Mulliken JB, Stal S, Finnell RH, Hecht JT.
Folate pathway and nonsyndromic cleft lip and palate.
Birth Defects Res A Clin Mol Teratol. 2011 Jan;91(1):50-60. doi: 10.1002/bdra.20740. Epub 2010 Dec 1.
PMID: 21254359    

Dai D, Zhu H, Wlodarczyk B, Zhang L, Li L, Li A, Finnell RH, Roop DR and J Chen.
Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia.
J. Invest. Derm. 2011 Feb;131(2):302-10. doi: 10.1038/jid.2010.306. Epub 2010 Oct 21.
PMID: 20962855

2010

 

Finnell RH, Blom HJ,Shaw GM
Does global hypomethylation contribute to susceptibility to neural tube defects?
Am J Clin Nutr. 2010 May;91(5):1153-1154. doi: 10.3945/ajcn.2010.29534. Epub 2010 Apr 7.
PMID:20375188    

Iskandar BJ, Rizk E, Meier B, Hariharan N, Bottiglieri T, Finnell RH, Jarrard DF, Banerjee RV, Skene JHP, Nelson A. et al.
Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation.
J Clin Invest. 2010 May;120(5):1603-1616. doi: 10.1172/JCI40000. Epub 2010 Apr 26.
PMID:20424322    

Obican SG, Finnell RH, Mills JL, Shaw GM, Scialli AR.
Folic acid in early pregnancy: a public health success story.
FASEB J. 2010 Nov;24(11):4167-4174. doi: 10.1096/fj.10-165084. Epub 2010 July 14.
PMID: 20631328  

2009

 

Salbaum, J. M., Finnell, R. H. and Kappen, C.
Regulation of folate receptor 1 gene expression in the visceral endoderm.
Birth Defects Res A Clin Mol Teratol. 2009 Apr;85(4):303-313. doi: 10.1002/bdra.20537.
PMID:19180647  

Shaw, G.M., Lu, W., Zhu, H., Yang, W., Briggs, F.B., Carmichael, S.L., Barcellos, L.F., Lammer, E.J., and Finnell, R.H.
118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects.
BMC Med Genet. 2009 Jun 3;10:49. doi: 10.1186/1471-2350-10-49.
PMID:19493349